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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
18/04/2023 |
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Data da última atualização: |
15/01/2024 |
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Tipo da produção científica: |
Capítulo em Livro Técnico-Científico |
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Autoria: |
CORREIA, B. S. B.; DALLE PIAGE, P. M. F.; ALMEIDA, L. S.; RIBEIRO, G. H.; PEIXOTO, C. S.; COLNAGO, L. A.; CARDOSO, D. R. |
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Afiliação: |
LUIZ ALBERTO COLNAGO, CNPDIA. |
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Título: |
The Use of NMR Based Metabolomics to Discriminate Patients with Viral. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
In: COVID-19 Metabolomics and Diagnosis: Chemical Science for Prevention and Understanding Outbreaks of Infectious Diseases. Cham: Springer International Publishing, 2023. |
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Páginas: |
129 - 174 |
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ISBN: |
978-3-031-15889-6 (eletrônico) |
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DOI: |
https://doi.org/10.1007/978-3-031-15889-6_7 |
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Idioma: |
Inglês |
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Conteúdo: |
Infectious diseases are one of the most common conditions impacting global health, being a matter of concern for health agencies due to their contagious capacity and periodic outbreaks of new diseases, such as the global pandemic COVID-19. Viruses are among the main causes of this illness and it is defined as obligate intracellular parasites for their need to have a host cell to live and reproduce, since they won?t produce proteins and compete for nutrients and metabolites leading to the alteration of the host metabolome. The diagnosis of these viral infections can be done by detecting viral particles or components, isolating the virus in cell culture, or even by evaluating immune responses. In this context, metabolomics comes as a very useful tool that reflects all ?omics? techniques and best represents the phenotype. Since water-soluble metabolites and lipids are the major molecular constituents of human plasma, their abnormalities are commonly observed during disease, which contributes to the understanding of physiology and pathology. Nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) are the most widely used techniques in metabolomics. NMR spectroscopy has emerged as a valuable application due to its ability to identify compounds with simple sample preparation, in addition, to being a non-destructive, highly reproducible, and quantitative technique (primary ratio method). These features make NMR a valuable tool that is frequently used in metabolomics analysis, and nowadays used in the diagnosis of viral diseases. Therefore, in this chapter, we will address a short integrative description of viral diseases and diagnostics, metabolomics, and NMR concepts. Furthermore, we will explore the advances in NMR-based metabolomics applied in medicine, and finally, the viral diseases discriminated by NMR-based metabolomics. MenosInfectious diseases are one of the most common conditions impacting global health, being a matter of concern for health agencies due to their contagious capacity and periodic outbreaks of new diseases, such as the global pandemic COVID-19. Viruses are among the main causes of this illness and it is defined as obligate intracellular parasites for their need to have a host cell to live and reproduce, since they won?t produce proteins and compete for nutrients and metabolites leading to the alteration of the host metabolome. The diagnosis of these viral infections can be done by detecting viral particles or components, isolating the virus in cell culture, or even by evaluating immune responses. In this context, metabolomics comes as a very useful tool that reflects all ?omics? techniques and best represents the phenotype. Since water-soluble metabolites and lipids are the major molecular constituents of human plasma, their abnormalities are commonly observed during disease, which contributes to the understanding of physiology and pathology. Nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) are the most widely used techniques in metabolomics. NMR spectroscopy has emerged as a valuable application due to its ability to identify compounds with simple sample preparation, in addition, to being a non-destructive, highly reproducible, and quantitative technique (primary ratio method). These features make NMR a valuable tool that is frequently used in metabolomic... Mostrar Tudo |
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Palavras-Chave: |
NMR; Viral diseases. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02696naa a2200241 a 4500
001 2153223
005 2024-01-15
008 2023 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1007/978-3-031-15889-6_7$2DOI
100 1 $aCORREIA, B. S. B.
245 $aThe Use of NMR Based Metabolomics to Discriminate Patients with Viral.$h[electronic resource]
260 $c2023
300 $a129 - 174
520 $aInfectious diseases are one of the most common conditions impacting global health, being a matter of concern for health agencies due to their contagious capacity and periodic outbreaks of new diseases, such as the global pandemic COVID-19. Viruses are among the main causes of this illness and it is defined as obligate intracellular parasites for their need to have a host cell to live and reproduce, since they won?t produce proteins and compete for nutrients and metabolites leading to the alteration of the host metabolome. The diagnosis of these viral infections can be done by detecting viral particles or components, isolating the virus in cell culture, or even by evaluating immune responses. In this context, metabolomics comes as a very useful tool that reflects all ?omics? techniques and best represents the phenotype. Since water-soluble metabolites and lipids are the major molecular constituents of human plasma, their abnormalities are commonly observed during disease, which contributes to the understanding of physiology and pathology. Nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) are the most widely used techniques in metabolomics. NMR spectroscopy has emerged as a valuable application due to its ability to identify compounds with simple sample preparation, in addition, to being a non-destructive, highly reproducible, and quantitative technique (primary ratio method). These features make NMR a valuable tool that is frequently used in metabolomics analysis, and nowadays used in the diagnosis of viral diseases. Therefore, in this chapter, we will address a short integrative description of viral diseases and diagnostics, metabolomics, and NMR concepts. Furthermore, we will explore the advances in NMR-based metabolomics applied in medicine, and finally, the viral diseases discriminated by NMR-based metabolomics.
653 $aNMR
653 $aViral diseases
700 1 $aDALLE PIAGE, P. M. F.
700 1 $aALMEIDA, L. S.
700 1 $aRIBEIRO, G. H.
700 1 $aPEIXOTO, C. S.
700 1 $aCOLNAGO, L. A.
700 1 $aCARDOSO, D. R.
773 $tIn: COVID-19 Metabolomics and Diagnosis: Chemical Science for Prevention and Understanding Outbreaks of Infectious Diseases. Cham: Springer International Publishing, 2023.
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Registro original: |
Embrapa Instrumentação (CNPDIA) |
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| Registros recuperados : 17 | |
| 1. |  | FRANCISCO, V. C.; OKUMURA, F.; TULLIO, R. R.; BERNDT, A.; CARDOSO, D. R.; NASSU, R. T. Análise de compostos voláteis de carne bovina proveniente de animais alimentados com erva-mate (Ilex Paraguariensis st. Hilare). In: CONGRESSO BRASILEIRO DE CIÊNCIA E TECNOLOGIA DE ALIMENTOS, 26., 2018, Belém, PA. Anais... Belém, PA: CBCTA, 2018. Código do trabalho 3467.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 3. | | CORDEIRO, C. S.; CARDOSO, D. R.; CAVALLINI, D. C. U.; NASSU, R. T. Effect of UV-C light irradiation on the structure and microbiological quality of whey from bovine milk. In: REUNIÃO DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 57., 2022, Campinas. Tropical animal science and pratice to feed the planet: proceedings. Brasília, DF: SBZ; São Carlos, SP: Embrapa Pecuária Sudeste, 2022. p. 326.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 7. | | CERIBELI, C.; ZAWADZKI, A. de; RACANICCI, A. M. C.; COLNAGO, L. A.; SKIBSTED, L. H.; CARDOSO, D. R. Mate as dietary supplement for broiler chickens: effect on the metabolic profile and redox chemistry of meat. Journal of the Brazilian Chemical Society, v. 29, n. 11, p. 2266-2277, 2018.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Instrumentação. |
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| 8. | | NASSU, R. T.; TULLIO, R. R.; BERNDT, A.; SILVA, M. L. P. da; VIDAL, M. P.; CARDOSO, D. R. Sensory descriptive analysis and acceptance of beef From animals fed yerba mate. In: INTERNATIONAL CONGRESS OF MEAT SCIENCE AND TECNOLOGY, 60., 2014, Punta del Este. Anais... Punta Del Este: ICMST, 2014.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 10. | | RODRIGUES, B. M.; ALVARENGA, R. C.; LANNA, D. P. D.; OLIVEIRA, A. de L.; CERIBELIE, C.; CORREIA, B. S. B.; COLNAGO, L. A.; CARDOSO, D. R.; SOUZA, F. A. de; LOPES, L. S. Aged-beef quality and fatty acid profile of subcutaneous fat from Nellore and Nellore × Angus crossbred young bulls finished in the feedlot with a high-lipid diet. Animal Production Science, v. 64, n. 1, AN23165, 2024.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Instrumentação; Embrapa Milho e Sorgo. |
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| 11. | | MALHEIROS, J. M.; CORREIA, B. S. B.; CERIBELI, C.; CARDOSO, D. R.; COLNAGO, L. A.; BOGUSZ JUNIOR, S.; REECY, J. M.; MOURÃO, G. B.; COUTINHO, L. L.; PALHARES, J. C. P.; BERNDT, A.; REGITANO, L. C. de A. Comparative untargeted metabolome analysis of ruminal fluid and feces of Nelore steers (Bos indicus). Scientific Reports, v.11, n.1, e12752, 2021. 13 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 12. | | MALHEIROS, J. M.; CORREIA, B. S. B.; CERIBELI, C.; CARDOSO, D. R.; COLNAGO, L. A.; BOGUSZ JUNIOR, S.; REECY, J. M.; MOURÃO, G. B.; COUTINHO, L. L.; PALHARES, J. C. P.; BERNDT, A.; REGITANO, L. C. de A. Comparative untargeted metabolome analysis of ruminal fuid and feces of Nelore steers (Bos indicus). Scientific Reports, v. 11, n. 1, e12752, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação; Embrapa Pecuária Sudeste. |
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| 13. | | LOBO, R. R.; CORREIA, B. S. B.; PEÑA-BERMÚDEZ, Y. A.; VINCENZI, R.; SILVA, C. M. da; PANOSSO, L. L.; COLNAGO, L. A.; CARDOSO, D. R.; BERNDT, A.; PINHEIRO, R. S. B.; BUENO, I. C. da S.; FACIOLA, A. P. Effects of dietary inclusion of yerba mate (Ilex paraguariensis) extract on lamb muscle metabolomics and physicochemical properties in meat. Journal of Animal Science, v. 99, n. 9, 2021. 1-14| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação. |
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| 14. | | ZAWADZKI, A.; ARRIVETTI, L. O. R.; VIDAL, M. P.; CATAI, J. R.; NASSU, R. T.; TULLIO, R. R.; BERNDT, A.; OLIVEIRA, C. R.; FERREIRA, A. G.; NEVES-JUNIOR, L. F.; COLNAGO, L. A.; SKIBSTED, L. H.; CARDOSO, D. R. Mate extract as feed assitive for improvement of beef quality. In: FOOD RESEARCH INTERNATIONAL, v. 99, p. 336-347, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação. |
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| 15. | | LOBO, R. R.; CORREIA, B. S. B.; PEÑA-BERMÚDEZ, Y. A.; VINCENZI, R.; SILVA, C. M. da; PANOSSO, L. L.; CERIBELI, C.; COLNAGO, L. A.; CARDOSO, D. R.; BERNDT, A.; PINHEIRO, R. S. B.; BUENO, I. C. da S.; FACIOLA, A. P. Effects of dietary inclusion of yerba mate (Ilex paraguariensis) extract on lamb muscle metabolomics and physicochemical properties in meat. Journal of Animal Science, v. 99, n. 9, 2021. 1-14| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 16. | | ZAWADZKI, A. de; ARRIVETTI, L. de O. R.; VIDAL, M. P.; CATAI, J. R.; NASSU, R. T.; TULLIO, R. R.; BERNDT, A.; OLIVEIRA, C. R. de; FERREIRA, A. G.; NEVES JUNIOR, L. F.; COLNAGO, L. A.; SKIBSTED, L. H.; CARDOSO, D. R. Mate extract as feed additive for improvement of beef quality. Food Research International, v. 99, p. 1-13, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 17. | | MALHEIROS, J. M.; CORREIA, B. S. B.; CERIBELI, C.; BRUSCADIN, J. J.; DINIZ, W. J. S.; BANERJEE, P.; VIEIRA, D. S.; CARDOSO, T. F.; ANDRADE, B. G. N.; PETRINI, J.; CARDOSO, D. R.; COLNAGO, L. A.; BOGUSZ JUNIOR, S.; MOURÃO, G. B.; COUTINHO, L. L.; PALHARES, J. C. P.; MEDEIROS, S. R. de; BERNDT, A.; REGITANO, L. C. de A. Ruminal and feces metabolites associated with feed efciency, water intake and methane emission in Nelore bulls. Scientifc Reports, v. 13, 18001, 2023. 13 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Instrumentação; Embrapa Pecuária Sudeste. |
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| Registros recuperados : 17 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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